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Diabetic Limb Salvage and Wound Healing

Diabetes-related foot wounds and infections can threaten mobility, independence, and quality of life. Our research seeks to improve their prevention, diagnosis, and treatment, with the goal of achieving lasting healing, reducing avoidable amputations, and preserving function.

Research guided by clinical questions

Our work begins with the challenges encountered in caring for patients with complex lower extremity wounds.

  • Why do some wounds fail to heal or repeatedly return?
  • How can we identify and treat infection more effectively?
  • Which medical and surgical approaches offer the best opportunity for recovery?

We address these questions through clinical trials, studies of patient outcomes, and translational investigations that connect biological mechanisms with clinical care. Our research examines factors that influence healing and infection, evaluates established and emerging treatments, and investigates approaches to diabetic limb preservation. Collaboration across surgical, medical, and scientific disciplines helps us study these problems from complementary perspectives.

Contributing to evidence-based care

Our investigators have contributed to peer-reviewed research and professional treatment guidance, including the Wound Healing Society guidelines for diabetic foot ulcer treatment. These contributions reflect our commitment to developing evidence that clinicians can use to make better decisions for patients.

Research also forms an integral part of our Diabetic Limb Salvage Fellowship. Through mentorship and participation in clinical investigation, fellows learn to critically evaluate evidence and address unanswered questions in wound care and limb preservation.